Resistance to one or more antibiotics can be transmitted from one bacterial strain to a related but previously sensitive strain by bacteriophage transduction. It is not clear yet whether this mechanism is an important source of therapeutic difficulties. Transferable or infective resistance presents a threat to antibiotic control of all infectious diseases. It is important for the following reasons:
patients who are distributing these strains into their environments; always giving anti-bacterial drugs in adequate doses; and using drug combinations when appropriate. Another approach to the problem that has had some successes is to introduce an antibiotic policy for a hospital or area. This usually involves designating certain antibiotics as available for general use but withdrawing others from circulation or permitting their use only on rare and special occasions. If all goes well (and in particular, if all relevant clinicians abide by the policy), the incidence of strains resistant to the reserved antibiotics falls considerably in the months following institution of the policy, and in due course it may be judged right to reintroduce these drugs for general use and to withdraw others.
Has a vast experience in medical bacteriology